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5-HTP Supplement Review

NutraChamps 5-HTP
Arazo Nutrition 5-HTP

Our Review of 5-HTP

5-Hydroxytryptophan or 5-HTP is a compound naturally produced in the body from the amino acid tryptophan. It is a precursor to the neurotransmitter serotonin. Unfortunately, sometimes there is not enough 5-HTP in our bodies, so we need a little help.

An excellent natural source for 5-HTP can be obtained from the seed of the African shrub Griffonia simplicifolia.

Basic info on 5-HTP

Based on scientific research, 5-HTP has been seen as a treatment for anxiety, depression, migraines, insomnia, fibromyalgia, and hot flashes, as it increases the serotonin level in the brain.

Benefits of 5-HTP

Anxiety, Depression and Panic Attacks

In this article, our main focus is on the treatment of anxiety. While we know that 5-HTP is not the only amino acid supplement used as an alternative treatment for anxiety, we do know that more research has been carried out on it than the others.

Animal studies and human clinical trials have both shown that 5-HTP has anti-anxiety effects. There is some evidence that 5-HTP may inhibit panic attacks. It is highly effective against chronic generalized anxiety.

Research has shown that 5-HTP has been determined as a safe alternative to antidepressants with fewer side effects especially when taken in the right dosage or as prescribed by your health specialist.


5-HTP helps resolve the root cause of insomnia because of the increase of serotonin - which is then converted to melatonin - the hormone essential to the handling of the sleep-wake cycle. 

Increasing melatonin has been shown to break the insomnia cycle and regulate sleep patterns.

Blood Sugar, Low-Carb, Keto and Weight Loss

Another wonderful benefit of 5-HTP affecting serotonin in the brain is it may increase feelings of fullness, thereby helping you to eat less and lose weight. Likewise, 5-HTP has been shown to help with the control of blood sugar which is beneficial for everyone, and especially diabetics.

The results in one study showed that those who took 5-HTP ate 435 fewer calories per day, on average, and in particular inhibited the intake of calories from carbohydrates. This would be beneficial to those on low-carb or keto diets.

Stressed, anxious, or depressed people usually eat more, and many times things that are not healthy for them, and then, unfortunately, gain weight. But the good news is researchers have determined there is a parallel between 5-HTP serotonin production reducing stress and depression, to the reduction of stress eating, to then achieving weight loss.

General Health

Research and testing show that 5-HTP is effective against severe migraine headaches. Results showed it reducing the regularity of the migraine attacks, as well as, the severity of the attacks.

Just as well 5-HTP is very effective against fibromyalgia. A condition with characteristics such as fatigue, pain in the ligaments, muscles, and tendons. A recent study in Texas that involved 50 people with this condition were treated with 5-HTP for a month. Amazingly, in all the patients there was a reduction in pain, fatigue, and anxiety.

Note: If you have a surgery scheduled, it would be wise for you to stop taking 5-HTP for at least a week or two before getting the surgery. This is because you need to let your serotonin levels go back to their ‘normal range’. These levels can be affected during surgery. This would help to avoid complications that might occur with your mood after surgery.

Pros and Cons of 5-HTP


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    It helps to control anxiety & depression
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    It is effective in incidents of panic attacks
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    It helps to resolve the issue of insomnia
  • It is effective against migraines
  • It is effective against fibromyalgia
  • It improves moods


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    It is not safe when taken by in very large doses (6-10 grams) which can cause nausea, muscle spasms & severe stomach problems
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    Do not take 5-HTP with another antidepressant, as it can lead to serious complications
  • The combination of 5-HTP with certain other drugs can cause heart problems – check with your physician

Suggested Dosages and Use

For anxiety, stress, depression, and mood take a minimum of 200 mg to 300 mg, 3 times per day with meals.

For weight management take 250 mg to 300 mg, 30 minutes prior to each meal.

For fibromyalgia relief take 100 mg, 3 to 4 times per day with meals.

For migraines take 100 mg to 200 mg, 2 to 3 times per day with meals.

For insomnia take 100 mg to 300 mg, 30 to 45 minutes before bed. Consider adding GABA to increase success.

Good results for some people have shown up same day or in a few days, for others it might be a week or two. This will always vary from person to person and dosage taken, so always allow at least 30 days to see full potential.

In Summary

5-HTP is a wonderful Supplement that can not only help in the relief of stress, anxiety, and depression, but also has many valuable attributes for both body and mind.

Have you been searching for suitable products on the internet or social media?

When you finally decide on a supplement, how do you know which of the many choices available is the Best to choose?

Allow us to aid your search by introducing the top two 5-HTP products that we have tried and know they work.

Here are the two Top-Rated Brands that we recommend and have found to be the Best



Our Rating

NutraChamps 5-HTP
NutraChamps 5-HTP
  • Naturally Supports Brain, Mood & Sleep
  • Calm & Relaxing Boost
  • Natural source for production of Serotonin

4.6 out of 5

Arazo Nutrition 5-HTP
Arazo Nutrition 5-HTP
  • Improve Mood & Positive Outlook
  • Relieve Anxiety & Stress
  • Promotes Relaxation of Mind & Body

4.4 out of 5

Our Conclusions

In our Review of 5-HTP, we found it to be a wonderful supplement with many benefits in addition to reducing stress and anxiety.

We believe it would be a great addition into anyone's daily regimen of the Best Supplements for Health and Life.