
According to the World Health Organization (WHO), close to 300 million people across the world have an anxiety disorder, with the United States accounting for about 40 million cases. The disorder can strike anyone at any age although women are two times as likely to develop anxiety disorders as men.
Medical experts have not yet fully discovered the exact causes of anxiety disorders, but some life experiences, especially traumatic events can be the root cause. Stress from an illness, inherited traits, personality, drug or alcohol abuse, work, and life pressures, in general, can also be contributing factors.
It’s normal to experience occasional anxiety, but if the symptoms become frequent, intensive, and excessive, the persistent fear, worry, and even panic can greatly interfere with your daily activities. This can negatively impact all aspects of your life.
Do you experience too many migraines or have a problem sleeping?
Do you feel like you get too worried, stressed or anxious about things?
Do you experience depression?
These may all be symptoms of anxiety and stress disorders that need to be taken care of as soon as possible before things get worse. If these symptoms are not treated, they can often result in chronic illnesses like heart disease, cancer, and sometimes death.
Lifestyle changes, counseling, meditation, prescribed medications, and exercises have reportedly helped some people to cope with anxiety, stress, and depression.
Fortunately, there is mounting evidence that certain natural supplements combined with lifestyle changes can be extremely effective in the prevention and treatment of anxiety, stress, and depression, without causing the adverse side effects that sometimes occur with certain medications.
Research shows that the symptoms of anxiety, stress, and depression result from an alteration of the body’s chemistry. Herbal supplements, taken in the right combination and doses, work to reverse these alterations and normalize body functions.

From our own personal experience, along with many others, we have found the best way to do this is by consuming a daily regimen of herbal Supplements and Vitamins along with a healthy diet to achieve a balanced body and mind.
In this synopsis, we will be reviewing with you, the Top 20 Best Supplements that you can find to reduce Anxiety and Stress. And, with each of the Top 20, we will recommend the Top 2 Products that we have found to be Best in each area. So, in Total, 40 Best Supplements and Vitamins.
While all 20 Supplements (total 40 Products) are Great, here's our
QUICK PICK
Top of the Top 5 Natural Supplements for Anxiety, Stress and Depression
Product | Details | Our Rating |
---|---|---|
Physician's CHOICE Organic Ashwagandha Root | 4.6 out of 5 | |
NatureBell Organic Bacopa Monnieri | 4.7 out of 5 | |
Nobi Nutrition High Absorption Magnesium Complex | 4.8 out of 5 | |
Toniiq Triple Strength Polynesian Kava Kava | 4.0 out of 5 | |
Now GABA | 4.3 out of 5 |
Be sure to take your time and review all of the Supplements and Vitamins, below, to see what you find to be the Best of the Best for you - so you can make the most informed and Best decision for your Health and Life.
Quick Navigation
- 1 Top of the Top 5 Natural Supplements for Anxiety, Stress and Depression
- 2 1. Ashwagandha
- 3 2. Rhodiola Rosea
- 4 3. Valerian Root
- 5 4. Bacopa
- 6 5. Magnesium
- 7 6. L-Theanine
- 8 7. Kava Kava
- 9 8. Lavender Oil
- 10 9. Passion flower
- 11 10. Chamomile
- 12 11. Lemon balm
- 13 12. GABA
- 14 13. 5-HTP
- 15 14. St. John’s Wort
- 16 15. Vitamin A
- 17 16. Vitamin B-Complex
- 18 17. Vitamin C
- 19 18. Vitamin D
- 20 19. Vitamin E
- 21 20. Fish Oil
- 22 Conclusions
1. Ashwagandha
Ashwagandha is an herb originating in India, which is also referred to as “Indian ginseng” or “Winter Cherry”. It is widely used for its “Rasayana” properties — it is said to have the ability to lengthen lifespan, restore the terminally-ill back to full health, and youthfulness back to the aged.
It is an adaptogen, it helps your body rid itself of stress which is an essential requirement for all human survival, especially in this day and age.
Ashwagandha aids in alleviating the stress that accumulates in your body, improves your mood, and enhances your stamina. It is wonderful for treating irritability or sleep disorders, which is one of the dominant side effects experienced by chronic stress.
Ashwagandha supports the cortisol and adrenal functions of your body by normalizing the body chemistry that stress and anxiety have altered; thus, returning your body functions back to optimal levels.
Lastly, Ashwagandha possesses a known benefit of aiding in the relief and affliction of joint pains, muscle pains, and inflammation.
Ashwagandha is a wonderful supplement with many benefits in addition to reducing stress and anxiety.
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2. Rhodiola Rosea
Rhodiola Rosea grows naturally in the wild in the Arctic regions of the world. It is an adaptogen that has been used as a supplemental product by the Chinese and the Greeks as far back as the first century A.D.
Rhodiola Rosea has the potential of alleviating fatigue, moodiness, and tiredness, as well as, anxiety and stress that you might feel at any point in time.
If your work requires a great deal of physical energy, the supplement is perfect for giving a much-needed energy boost to keep you going.
Its muscle recovery properties — its ability to regenerate RNA, enzymes, and proteins in muscle mass — continue to make it a favorite amongst top-notch athletes and bodybuilders.
It is also a known “nootropic”, able to boost your cognitive abilities — memory, associative thinking, control, concentration, and capacity for mental work. With all its wonderful attributes, Rhodiola Rosea is an excellent choice to reduce anxiety and stress.
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3. Valerian Root
Valerian Root, known as “all-heal” or “garden heliotrope”, grows in the EU, North America, and Asia. It has three key components that account for its wide-ranging effects — valerenic acid, which increases GABA levels in the brain; iridoids, known for their sedative effects; and isovaleric acid, which hinders uncontrolled muscle contractions.
Here are a few of the many wonderful benefits in taking Valerian Root:
- As a sedative Valerian Root will improve your sleep.
- Valerian Root is perfect for alleviating the symptoms of stress and anxiety you feel.
- Valerian Root improves your memory and cognitive functions.
- Valerian Root improves your heart health by lowering your blood pressure.
- Valerian Root will help you if you experience menstrual cramps or menopausal symptoms like hot flashes because of its muscular spasm suppression properties.
- Valerian Root improves treatment in children or adults battling Attention Deficit Disorder (ADD) and Attention Deficit Hyperactivity Disorder (ADHD).
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4. Bacopa
Bacopa monnieri is a vital herb that “creeps” across the wetlands of the earth. It has been used for centuries as a tranquilizer and also for its cognitive properties. Ancient Vedic scholars memorized lengthy sacred hymns and scriptures using the supplement.
Taken in regulated doses, it will balance out your immune system and help combat diabetes and cancer in your body. As a “brain food”, it will keep your brain nourished, and your memory and intelligence at an optimum. It helps to prevent the onset of Parkinson’s and Alzheimer’s in your body.
It is also known as an excellent antioxidant, anti-inflammatory, and anti-stress supplement. Likewise, it’s good for the health of your heart, as it prevents heart attacks and normalizes high blood pressure by dissolving blood clots.
Helping your body in so many ways, as well as, helping memory and reducing stress and anxiety, Bacopa supplements are an excellent choice.
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5. Magnesium
Magnesium is essential for your body’s cell-to-cell communication, powering more than three hundred different enzymes. It is so important, that without it, no physiological function in your body will work.
Magnesium improves the muscle function of your body, ensures the integrity of your bone structure, and restores your bone mass. Which is critical for both men and women - but even more so if you are a postmenopausal woman.
Additionally, it protects your heart against disease by preventing blood platelets from collecting together. It helps your body with its use of insulin, thus helping to guard it against diabetes. It protects your kidney functions from declining. It also reduces your blood pressure. Applied topically on your skin, it will cure you of several skin allergies and rejuvenate your skin.
Likewise, Magnesium will relieve you of headaches, migraines, chronic fatigue, as well as, anxiety and depression.
With all the marvelous benefits of Magnesium, beyond reducing stress and anxiety, it is a must-have supplement for your overall health.PROS
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6. L-Theanine
L-Theanine is the amino acid commonly found in tea leaves, green tea and in some mushrooms. It’s used as a stimulant for improving moods and lowering stress. It does this by crossing from the bloodstream into the brain to directly target chemicals found there.
Taking L-Theanine will make you feel less anxious and less stressed. Your heart rate and blood pressure will go down.
It does this by enhancing nitric oxide production. Your brain functions will improve, your attention span will increase, and your memory will be enhanced; especially when you ingest it with caffeine.
Regularly taking L-Theanine supplements will increase your quality of sleep, reduce symptoms of mental disorders, enhance your immunity against infection and tumors and help eliminate depressive moods.
Enhancing your memory along with its many other benefits, L-Theanine is an excellent supplement in your arsenal in reducing stress and anxiety.
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7. Kava Kava
Kava Kava is extracted from the kava plant that grows as a shrub in the South Pacific region. Its roots are traditionally mixed with water to form a psychotropic beverage.
It has two active agents— kavalpyrones, which are able to induce muscles to relax and hence bring about a calming effect on the body; and chalcones, which fight off cancerous cells, and have antioxidant, anti-inflammatory, and antimicrobial properties.
It can help in receding cancers from your body. It relieves you of anxiety, depression, and cures you of many sleep disorders. Likewise, it improves brain function and protects it against the onset of degenerative diseases like Parkinson’s and Alzheimer’s. It can also aid in the cure of any addiction you are suffering from, by increasing the dopamine in your brain.
Kava Kava is a wonderful supplement aiding your body in many ways, as well as, in the reduction of stress and anxiety, making it an excellent choice when taken in prescribed dosages.PROS
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8. Lavender Oil
Lavender’s main ingredients are linalool and linalyl acetate. Linalool is an anti-conflict agent, while both, used together have sedative effects.
If you take Lavender as a supplement, you will experience a marked reduction in the level of stress that you feel. It also works to reduce any anxiety or depression that you feel by increasing your brain’s alpha and theta waves that in turn cause you to relax.
It will improve your sleep quality, and enhance your cognitive abilities; especially if you suffer from a degenerative disease.
Lavender is a good antioxidant and an anti-inflammatory agent when you apply it topically or through injections. It can help heal your wounds and help eliminate any pains or itchiness that you feel. Likewise, it can help alleviate menstrual cramps, as well as, help eliminate headaches.
With all its benefits, including reducing stress, anxiety, and depression, Lavender supplements are an excellent choice.
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9. Passion flower
Passion flower or Passionflower has been groomed by Native American Indians for centuries. Their cultures, along with others, have cherished its value. With over 500 known species of the plant in the world, it can be distinguished by its beautiful flowers and by the sweet fruit it produces.
It has numerous health benefits.
It is known to have valuable effects in delaying the progression of chronic diseases like Alzheimer’s, Parkinson’s and cancers.
Passionflower is known to help relieve menopausal women of hot flashes.
Amazingly, it works well in aiding children and adults in the reduction of Attention Deficit Hyperactivity Disorder (ADHD) and Attention Deficit Disorder (ADD).
Likewise, you can take Passionflower extracts to aid in the relief of anxiety, stress, substance addiction, and sleep disorders.
Bringing valuable aid in reducing stress and anxiety, Passionflower supplements can be an excellent choice for you.
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10. Chamomile
Chamomile is a medicinal plant that has been around for thousands of years. Its active components give it its unique pharmacological properties.
It contains terpenoids, an antioxidative and anti-inflammatory compound that can prevent the formation of cancer cells and relieves pain. It also contains flavonoids, which are known to combat aging and oxidative stress, and in the relief of uncontrolled muscle movements.
If you consume Chamomile, you will begin to experience relief from inflammations, your skin can heal more quickly and the quality of your sleep will improve. In addition, you will begin to feel less anxious and many thoughts of depression will begin to disappear naturally.
If you suffer chronic illnesses like diabetes or cancers, regular intake of Chamomile will slow down their progression and may even aid in reversing them.
With all its benefits, as well as, reducing stress and anxiety, Chamomile supplements are an excellent choice you should consider.
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11. Lemon balm
Lemon balm is an herbal plant known for its unique smell. It is widely used for its calming and anti-inflammatory properties. Its active components are volatile compounds, triterpenes, and phenolics.
If you are susceptible to panic attacks and rapid heartbeats, a 14-day treatment course with Lemon balm will be beneficial to you. The same applies if you suffer from stress, depression or anxiety. Regular intake of Lemon balm will improve your memory and brain function and will make you sleep better.
Lemon balm can also help you lose excess weight, help cure you of non-alcoholic fatty liver disease, help alleviate type 2 diabetes and help stop the growth of several forms of cancers.
With all its wonderful benefits, along with reducing stress and anxiety, Lemon balm is an excellent supplement to try.
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12. GABA
GABA, or Gamma-aminobutyric acid, is a neurotransmitter that resides in the brain and functions as a “braking system for the mind”. When active, it slows down and calms the activities of the cells in the brain, bringing about a tranquil state of mind.
GABA is the counterbalance to glutamate, the brain’s most excitatory neurotransmitter. In fact, the brain produces GABA from glutamate. When both glutamate and GABA are at proper levels and in harmony, the brain functions well.
GABA can improve your mood, relief you of insomnia, and is anti-inflammatory. It can also reduce your stress level, take away your anxieties, take away depressive moods that you feel, and boost your cognitive abilities.
GABA is key in balancing your mental functions, and key in reducing anxiety, stress, and depression, making it a must-have in your arsenal of daily supplements.
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13. 5-HTP
5-HTP or 5-Hydroxytryptophan is the amino acid precursor of serotonin and is excellent for use in treating depression, anxiety, and sleep disorders. It also helps with weight loss.
5-HTP will help you combat panic attacks, stress, and anxiety when controlled doses are taken for upwards of six weeks. It can help children have fewer nightmares if you give them 2mg per kg of body weight just before they turn in to bed. 5-HTP improves the quality of sleep in adults.
In addition, you can take 5-HTP supplements to lose weight and it will help reduce your body’s sugar level if you are diabetic.
If you have panic attacks, as well as, stress and anxiety, 5-HTP supplements are an excellent choice.
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14. St. John’s Wort
St. John’s Wort is a medicinal plant with yellow flowers. It is used in teas, as well as, is readily available in tablet or capsule forms that contain pure extracts. It has two active agents which explain its highly desired supplemental properties — hypericin and hyperforin.
The hypericin agent will help you fight off depression by stimulating capillary blood flow. It will also regulate the amount of dopamine in your brain.
Hyperforin is not only highly regarded for its antidepressant action, but also used in the treatment of neurogenic pain. Also, Hyperforin is known to inhibit the growth of cancerous cells.
If you apply St. John’s Wort topically to cuts or wounds, it will kill all of the bacteria and viruses on the site. It will also reduce any inflammation there.
When taken regularly, St. John’s Wort can help delay the progression of degenerative diseases such as Alzheimer’s or Parkinson’s.
If you need to reduce depression, as well as, stress and anxiety, then regulating your brain functions by utilizing St. John’s Wort supplements are a must-have.
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15. Vitamin A
Vitamin A, also known as retinol, is crucial for the proper functioning of your immune system, skin, eyes, teeth, bones, and hormone formation. It protects your eyes and skin from ultraviolet damage and thereby helps prevents skin cancer.
Vitamin A empowers the operations of Vitamin D in your body. It is needed for your thyroid hormones to be effective. If you consume Vitamin A in modest amounts, it will boost your body’s immune system and may help you lose weight.
Vitamin A helps your body regulate glucose levels; thus, it can help prevent diabetes.
Vitamin A will likewise keep your brain functioning and keep your body’s circadian rhythm at an optimum, which in turn will help reduce anxiety and stress.
Helping Vitamin D enhance your brain, as well as, reducing stress and anxiety, Vitamin A supplements are a valuable choice.
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16. Vitamin B-Complex
Vitamin B-Complex is a collection of eight water-soluble vitamins that all play a role in converting food into energy in the body. Vitamin B-Complex includes B1 - thiamin, B2 - riboflavin, B3 - niacin, B5 - pantothenic acid, B6 - pyridoxine, B7 - biotin, B9 - folic acid, and B12 - cobalamin. Each B vitamin plays a specific role in the body and is packed together in the B-Complex supplement.
Vitamin B-Complex will fight off depression and anxiety in your body, usually signaled by low levels of vitamin B12.
It will also help your wounds to heal, as well as, oral ulcers. If you are a female who experiences premenstrual syndrome, taking it will help you alleviate its symptoms.
Lastly, Vitamin B-Complex can be helpful in the delay and progression of several chronic illnesses such as Crohn’s disease, kidney disease, heart disease, Alzheimer’s and HIV/AIDS.
Vitamin B-Complex is an extremely valuable supplement for both body and mind. With its wonderful qualities in reducing stress and anxiety, Vitamin B-Complex should be part of your daily supplement regimen.
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17. Vitamin C
Vitamin C or ascorbic acid is a micronutrient that is easily emulsified in water. It is the most effective antioxidant in the human body because of its water-solubility and the large numbers of oxygen radicals it can attack. In the simplest of terms, Vitamin C is absolutely great for your health.
Vitamin C helps all of your brain’s psychological processes and your body’s physiological processes function at their optimal best. It improves your mood, through the release of oxytocin, for those times when you are stressed, anxious or depressed.
Vitamin C reduces fatigue in your body and slows the decline in the cognitive function of the brain that results from aging. It improves blood flow, improves thyroid activity and combats several types of cancers.
Vitamin C is another “you can’t go wrong” extremely valuable supplement for both body and mind. With its wonderful qualities in reducing stress and anxiety, Vitamin C should be another part of your daily supplement regimen.
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18. Vitamin D
Vitamin D plays very important roles in bone health, nerves and muscle functions of your body. While readily available through sun exposure, proper precautions must be taken to not overexpose yourself to skin cancer or other skin conditions. Fortunately, there are excellent sources of Vitamin D supplements readily available to complement the sun.
Vitamin D keeps high blood pressure at bay, boosts your immunity, and optimizes cell production in your body. It likewise guards your body against the onset of diabetes by regulating insulin production.
Vitamin D is also active in the prevention and alleviating of the symptoms of several forms of cancers, as well as other chronic conditions, like lupus, heart disease, and infections.
Vitamin D balances out calcium and phosphorus production in the body. Also, Vitamin D in conjunction with Vitamin A helps with brain development and improves its cognitive functioning.
Add Vitamin D into your “you can’t go wrong” list of valuable supplements for both body and mind, and in reducing stress and anxiety. Make Vitamin D a definite part of your daily supplement regimen.
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19. Vitamin E
Vitamin E is a group of fat-soluble compounds that have unique antioxidant properties. It is a nutrient that plays an important role in sight, reproduction; as well as in the proper functioning of the skin, blood, and brain.
Vitamin E contains antioxidants that protect your body against free radicals which cause chronic illnesses like heart disease and cancers. It slows down the progression of Alzheimer’s and improves treatment outcomes in non-alcoholic liver disease. It is extremely valuable in helping to prevent you from having coronary heart disease, supports your immune function, prevents inflammation and promotes eye health.
If you are anemic, suffering nerve damage from chemotherapy, having painful menstruation, suffering from kidney disease or from rheumatoid arthritis, taking controlled doses of Vitamin E will help with the condition. Vitamin E is also extensively used in skincare.
A deficiency or inadequate levels of Vitamin E has been associated with increased anxiety and depression. Fortunately, to the opposite, maintaining proper consumption of natural Vitamin E supplements in the diet have been shown to help prevent anxiety, stress, and depression.
Vitamin E is another extremely valuable supplement for both body and mind. With its wonderful qualities in reducing stress and anxiety, Vitamin E should be added into your daily supplement regimen.
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20. Fish Oil
Fish oil is obtained from cold-water fish like salmon, mackerel, herring, and cod. It has two key components — eicosapentaenoic acid (EPA or Omega-3) and docosahexaenoic acid (DHA or Omega-6). Omega-3 and Omega-6 need to be present in the human body on a one to one ratio.
Ingesting proper dosages and types of Fish oil will help rid your body of migraines, muscle fatigue, infections, and help prevent cancers. Fish oil can increase fertility and help with fetal development. It protects your skin. Taken together with aspirin, it can reduce inflammation of most any body parts and relieve you of pain in your joints.
Fish oil has been shown to greatly reduce depressive thoughts in your mind by aiding in the relief of stress, anxiety and by lifting your mood. Likewise, it’s physiological advantages will reduce your risk of suffering a stroke because it improves blood flow to the brain.
Because of all of its psychological and physiological benefits to both your mind and body, reducing stress, anxiety, and depression, Fish oil supplements are an excellent choice to add into your diet.
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